N-4-CBZ-PIPERAZINE-2-CARBOXYLATE METHYL ESTER

N-4-CBZ-PIPERAZINE-2-CARBOXYLATE METHYL ESTER - Names and Identifiers

Name	4-Cbz-piperazine-2-carboxylate methyl ester
Synonyms	METHYL-4-CBZ PIPERAZINE-2-CARBOXYLATE MethylN-4-Cbz-piperazine-2-carboxylate 4-Cbz-piperazine-2-carboxylate methyl ester N-4-CBZ-piperazine-2-carboxyiate methyl ester N-4-CBZ-PIPERAZINE-2-CARBOXYLATE METHYL ESTER 1-benzyl 3-methyl piperazine-1,3-dicarboxylate 4-N-CBZ-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER 4-[(benzyloxy)carbonyl]piperazine-2-carboxylic acid Methyl 4-(benzyloxycarbonyl)piperazine-2-carboxylate PIPERAZINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER 3-METHYL ESTER
CAS	129799-11-7
InChI	InChI=1/C13H16N2O4/c16-12(17)11-8-15(7-6-14-11)13(18)19-9-10-4-2-1-3-5-10/h1-5,11,14H,6-9H2,(H,16,17)

N-4-CBZ-PIPERAZINE-2-CARBOXYLATE METHYL ESTER - Physico-chemical Properties

Molecular Formula	C14H18N2O4
Molar Mass	278.3
Density	1.212±0.06 g/cm3(Predicted)
Boling Point	406.5±45.0 °C(Predicted)
Flash Point	235.1°C
Vapor Presure	1.88E-09mmHg at 25°C
pKa	6.43±0.40(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.569

N-4-CBZ-PIPERAZINE-2-CARBOXYLATE METHYL ESTER - Introduction

Methyl N-4-Cbz-piperazine -2-carboxylate, chemical formula C19H19N3O4, is an organic compound.

Nature:
Methyl N-4-Cbz-piperazine-2-carboxylate is a solid having a white or off-white crystalline form. It is almost insoluble in water at normal temperature, but soluble in organic solvents such as ethanol, chloroform and dimethylformamide.

Use:
N-4-Cbz-piperazine-2-carboxylic acid methyl ester has important application value in organic synthesis. It can be used as an intermediate to participate in the synthesis of many drugs such as anti-epileptic drugs Parkinson's disease drugs. In addition, it can also be used in other organic synthesis reactions.

Preparation Method:
The synthesis of N-4-Cbz-piperazine-2-carboxylic acid methyl ester can be obtained by using piperazine and methyl formate. The specific process is that piperazine is reacted with methyl formate by heating under appropriate reaction conditions, and then the product is obtained by crystallization.

Safety Information:
The relevant safety information of N-4-Cbz-piperazine-2-carboxylic acid methyl ester is not clearly reported, so it is necessary to follow appropriate laboratory safety practices when using or handling it, and to operate according to the information provided in the chemical safety data sheet.

Last Update：2024-04-09 20:52:54